INSTITUTION · EU-OPENSCREEN

SINTEF

A EUREMAP partner providing 13 service(s) across 9 pipeline step(s).
NORWAY
Services offered
13
Pipeline steps
9/ 9
Research infrastructures
1
Country
Norway

About the institution

SINTEF is a EUREMAP partner contributing specialist marine natural product services to the federated catalogue.

Pipeline coverage

Genomics
3 services
Biomass production
1 services
Chemical Extraction
1 services
Bioassays & bioprofiling
2 services
Safety & toxicity
2 services
Chemical profiling
1 services
Chromatography
1 services
Structure elucidation
1 services
Synthesis
1 services

Services offered

  • Illumina and ONT sequencing with metagenome assembly, annotation, and genome analysis.
    Genomics
    Remote EU-OPENSCREEN
  • Automated metagenomic assembly and analysis pipeline based on Nextflow
    Genomics
    Remote EU-OPENSCREEN
  • Detection of BGCs using antiSMASH, BiG-SCAPE and Sanntis.
    Genomics
    Remote EU-OPENSCREEN
  • Cultivation of bacteria and fungi, 1 ml-50 L scale
    Biomass production
    Remote EU-OPENSCREEN
  • Extraction of cell pellets from cultures of up to 40 L.
    Chemical Extraction
    Remote EU-OPENSCREEN
  • Screening for antimicrobial, anticancer, antiviral, immunomodulatory and antioxidant bioactivities.
    Bioassays & bioprofiling
    Remote EU-OPENSCREEN
  • Dose-response bioactivity assays (MIC70 and anticancer cell viability assays)
    Bioassays & bioprofiling
    Remote EU-OPENSCREEN
  • Dose-response assay for human safety and ecotox assessment
    Safety & toxicity
    Remote EU-OPENSCREEN
  • In vivo safety assessment in mice, including compound concentration in blood and selected organs.
    Safety & toxicity
    Remote EU-OPENSCREEN
  • Chemical profiling using HPLC/UHPLC, RapidFire, DAD, QTOF, QQQ, FT-ICR-MS, MALDI and GC.
    Chemical profiling
    Remote EU-OPENSCREEN
  • Small-, medium- or large-scale fractionation and purification.
    Chromatography
    Remote EU-OPENSCREEN
  • Structure elucidation using LC-MS, LC-HRMS-MS/MS, MALDI-ESI and NMR.
    Structure elucidation
    Remote EU-OPENSCREEN
  • Chemical modification of natural compounds to improve their pharmaceutical properties
    Synthesis
    Remote EU-OPENSCREEN