INSTITUTION · EMBRC

Centro de Ciências do Mar do Algarve

A EUREMAP partner providing 12 service(s) across 6 pipeline step(s).
PORTUGAL
Services offered
12
Pipeline steps
6/ 9
Research infrastructures
1
Country
Portugal

About the institution

Centro de Ciências do Mar do Algarve is a EUREMAP partner contributing specialist marine natural product services to the federated catalogue.

Pipeline coverage

Genomics
0 services
Biomass production
0 services
Chemical Extraction
1 services
Bioassays & bioprofiling
5 services
Safety & toxicity
0 services
Chemical profiling
1 services
Chromatography
1 services
Structure elucidation
2 services
Synthesis
2 services

Services offered

  • Extraction of biomass and culture media at scales of up to 5 L.
    Chemical Extraction
    Physical EMBRC
  • ECIS (electric cell-substrate impedance sensing)-based measurement of TEER, proliferation, toxicity, wound healing and cell migration
    Bioassays & bioprofiling
    Physical Remote EMBRC
  • MTT Cell Metabolic Activity Assay
    Bioassays & bioprofiling
    Physical Remote EMBRC
  • Screening of chemicals/drugs eliciting cell signalling linked to receptor activation, customisable to user requirements
    Bioassays & bioprofiling
    Physical Remote EMBRC
  • Screening for antimicrobial, antifungal, lipase, chitinase, collaginase, proteinase, cellulase, amylase, antioxidant activities
    Bioassays & bioprofiling
    Physical Remote EMBRC
  • Dose-response safety assessment in human cell lines, including lung, liver, colon, monocyte, neurone, astrocytes and kidney models.
    Bioassays & bioprofiling
    Physical Remote EMBRC
  • Chemical profiling using UHPLC-HR-MS, UHPLC-HR-MSn, GC-HR-MS, 500 MHz NMR, IR and CD.
    Chemical profiling
    Physical Remote EMBRC
  • Small-, medium- or large-scale fractionation and purification.
    Chromatography
    Physical Remote EMBRC
  • Structure elucidation using LC-MS, LC-HRMS, IMS, NMR, IR, polarimetry and CD.
    Structure elucidation
    Physical Remote EMBRC
  • Stereochemistry and chiral analysis using chemical methods, optical rotation and chiral methods.
    Structure elucidation
    Remote EMBRC
  • Assessment of synthesis target and success probability; proposed alternatives. Synthesis of analogues and Fluorescent analogues.
    Synthesis
    Remote EMBRC
  • Chemical modelling using bioinformatics, chemical libraries, molecular docking and QSAR.
    Synthesis
    Remote EMBRC